Not enough to understand about threshold effect?? Here, I come to let you see a ‘picture’ that I promised to show..Ectually,the picture is just a picture of graph..Interesting right??Haha..
Knowledge of the slope is important in comparing the toxicity of various substances ( Figure above). For some toxicants a small increase in dose causes a large increase in response (toxicant A, steep slope). For other toxicants a much larger increase in dose is required to cause the same increase in response (toxicant B, shallow slope).
A threshold for toxic effects occurs at the point where the body's ability to detoxify a xenobiotic or repair toxic injury has been exceeded. For most organs there is a reserve capacity so that loss of some organ function does not cause decreased performance. For example, the development of cirrhosis in the liver may not result in a clinical effect until over 50% of the liver has been replaced by fibrous tissue.
Pen off.Tata
Resources :
Turk J. & Turk A.(1988).Environmental Science.4th Edition.United States of Amerika.Saunders College Publishing.
by : *eizzah*
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